Associations between apolipoprotein CIII concentrations and microalbuminuria in type 2 diabetes
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چکیده
منابع مشابه
Associations between apolipoprotein CIII concentrations and microalbuminuria in type 2 diabetes
Microalbuminuria (MAU) is a strong predictor of diabetic nephropathy (DN), which is the main cause of morbidity and mortality in patients with diabetes mellitus (DM). Dyslipidemia exists in the majority of patients with DM and contributes to micro- and macrovascular complications associated with DM. Apolipoprotein CIII (apoCIII) is an inhibitor of the activity of lipoprotein lipase, which metab...
متن کاملLowering apolipoprotein CIII delays onset of type 1 diabetes.
Serum levels of apolipoprotein CIII (apoCIII) are increased in type 1 diabetic patients, and when β cells are exposed to these diabetic sera, apoptosis occurs, an effect abolished by an antibody against apoCIII. We have investigated the BB rat, an animal model that develops a human-like type 1 diabetes, and found that apoCIII was also increased in sera from prediabetic rats. This increase in ap...
متن کاملMicroalbuminuria and macroalbuminuria in type 2 diabetes.
BACKGROUND Type 2 diabetes is the leading cause of end stage renal disease worldwide. Prevalence of diabetic nephropathy (DN) varies in the different ethnic groups. Nepal is country with great ethnic diversity. This study has been done to find the prevalence of microalbuminuria and macroalbuminuria in the two ethnic groups Jyapu and Brahmin. METHODS In our study we have included two ethnic gr...
متن کاملMicroalbuminuria in Type 2 Diabetes and Hypertension
A lbuminuria is a well-known predictor of poor renal outcomes in patients with type 2 diabetes and in essential hypertension (1–4). Albuminuria has also been shown more recently to be a predictor of cardiovascular outcomes in these populations (5– 8). There is emerging data that reduction of albuminuria leads to reduced risk of adverse renal and cardiovascular events (9–12). It has become incre...
متن کاملPreventing microalbuminuria in type 2 diabetes.
BACKGROUND The multicenter double-blind, randomized Bergamo Nephrologic Diabetes Complications Trial (BENEDICT) was designed to assess whether angiotensin-converting-enzyme inhibitors and non-dihydropyridine calcium-channel blockers, alone or in combination, prevent microalbuminuria in subjects with hypertension, type 2 diabetes mellitus, and normal urinary albumin excretion. METHODS We studi...
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ژورنال
عنوان ژورنال: Experimental and Therapeutic Medicine
سال: 2014
ISSN: 1792-0981,1792-1015
DOI: 10.3892/etm.2014.1830